Cost-effectiveness Analysis Ofvaccination against Rotavirus with Rix4414 in France
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چکیده
CER was 20 360,90 USD for one patient with viral load <50 copies/ml (16 462,65–41 640,81 USD in sensitivity analysis). Cost of one patient with achieved viral load <50 copies/ml was lower for ETR group. CONCLUSIONS: According to the model ETR seems to be much more effective than placebo with affordable CER incremental ratio. Evaluation of ETR treatment costeffectiveness in common practice in Russian health care is needed.
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Cost-effectiveness analysis of vaccination against rotavirus with RIX4414 in France.
BACKGROUND It is estimated that annually 300 000 cases of rotavirus-induced gastroenteritis (RVGE) occur in children aged up to 5 years in France. A two-dose vaccine against rotavirus infection (RIX4414; Rotarix, GlaxoSmithKline), has been shown to be highly effective against severe RVGE. OBJECTIVE This study evaluated the cost effectiveness of general vaccination against rotavirus using RIX4...
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The most common cause of severe diarrhea in infants and young children is rotavirus gastroenteritis (RVGE), which is associated with significant morbidity, healthcare resource use, and direct and indirect costs in industrialized nations. The monovalent rotavirus vaccine RIX4414 (Rotarix™) is administered as a two-dose oral series in infants and has demonstrated protective efficacy against RVGE ...
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